Botox® is one of those remarkable medications which was developed for one purpose and is being found useful for many others. Botox® was originally approved in 1989 by the U.S. Food & Drug Administration for to treat an eye blinking disorder(治療眼睛周圍的除紋). It is derived from the bacterium Clostridium Botulinum(肉毒桿菌), known as Botulinum Toxin Type A. Botox® is the brand name(商品名)
Botox® is therapeutic muscle-relaxing agent (肌肉鬆馳劑)that works at motor nerve endings (運動神經末稍)(nerves that lead to muscles). It is in a class of drugs called neurotoxins. It is highly purified and has a long track record of safety.
Botox® Cosmetic is a medication used for several cosmetic and therapeutic applications. It is a purified protein that smoothes the muscles by blocking nerve impulses. With a few tiny injections, Botox® Cosmetic blocks the release of acetylcholine(乙醯膽鹼), the chemical that causes muscles to contract. With less movement, the skin surface gradually smoothes out and the lines begin to fade.(讓肌肉少運動,使皮膚表面漸光滑,進而消除皺紋)
Botox® has been used therapeutically for over 16 years to treat a variety of medical conditions. It is approved in more than 75 countries. Botox® for therapeutic use remains one of the most widely researched medicines in the world.
The same product with dosing specific to glabellar lines(抬頭紋) was approved by the US Food and Drug Administration (FDA) in 2002 as Botox® Cosmetic for the temporary treatment of moderate to severe frown lines between the brows in people ages 18 to 65.
Besides the known cosmetic and therapeutic benefits of Botox®, smile esthetics can be enhanced dramatically in persons with excessive gingival display or "gummy" smiles.(露齦笑) Persons injected for such a condition also show diminishing of pronounced nasolabial folds.(消除明顯的鼻唇皺摺)
Usually there area none, expect perhaps for the minor pain at the Botox® injection site and at times, diminishing expression lines at the lower portion of their eyes.
Usually, beneficial effects are noticed within three to five days. Eventually, it begins to wear off. Typical treatment lasts four to six months
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